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SpatioIQTM Discovery See biology across data, space and scale. ClinIQTM Translation Turn biological insight toward clinical impact.
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What we're learning, published.

Our work across spatial biology, multi-omics, analytics and translational research, built alongside scientific and clinical collaborators.

See what we found ↓
Same B-cell count, different arrangement: organized near the tumor edge versus dispersed inside it.
In focus · Clinical Cancer Research · Aug 2026

Where the B-cells sit tells you something.

In Claudin 18.2-expressing gastric cancer, we mapped how tumor-infiltrating B-cells are spatially organized, and found that their arrangement, not just their presence, carries information a bulk count would miss.

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Our work in the wild.

Disease
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Peritoneal metastasis
Molecular Cancer · Sep 2026

Identification of novel paracrine therapeutic targets in peritoneal metastases through integrative proteotranscriptomic analysis of ascites

10.1186/s12943-026-02787-3 →
SpatioScoreTM
published as
ImmunoThresholdTM
Gastric cancer
Clinical Cancer Research · Aug 2026

Spatial organisation of tumor-infiltrating B-cells informs immune checkpoint inhibitor response in Claudin 18.2-expressing gastric cancer

10.1158/1078-0432.CCR-26-1382 →
SpatioScoreTM
published as
ImmunoThresholdTM
Colorectal cancer
Nature Communications · Apr 2026

Spatial predictors of response to chemo-immunotherapy in microsatellite stable metastatic colorectal cancer

10.1038/s41467-026-72204-2 →
SpatioScoreTM
published as
ImmunoThresholdTM
NK/T-cell lymphoma
Cancer Discovery · Oct 2025

Priming with DNMT Inhibitors Potentiates PD-1 Immunotherapy by Triggering Viral Mimicry in Relapsed/Refractory NK/T-cell Lymphoma

10.1158/2159-8290.CD-25-0587 →
SpatioScoreTM
published as
ImmunoThresholdTM
Peritoneal metastasis
Clinical Cancer Research · May 2025

Spatial heterogeneity, stromal phenotypes, and therapeutic vulnerabilities in colorectal cancer peritoneal metastasis.

10.1158/1078-0432.CCR-24-3780 →
SpatioScoreTM
published as
ImmunoThresholdTM
Nasopharyngeal carcinoma
Cell Reports Medicine · May 2025

Tumour immune microenvironment delineates progression trajectories of distinct nasopharyngeal carcinoma phenotypes.

10.1016/j.xcrm.2025.102143 →
SpatioScoreTM
published as
ImmunoThresholdTM
Gastric cancer
Cancer Discovery · Apr 2025

Spatially Resolved Tumor Ecosystems and Cell States in Gastric Adenocarcinoma Progression and Evolution

10.1158/2159-8290.CD-24-0605 →
SpatioVerseTM
published as
ImmunoVerseTM
SpatioScoreTM
published as
ImmunoThresholdTM
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